29 Oct '13, 6pm

How an iPod Could Transform Drug Testing

Researchers at Rice University and a Houston-based startup have developed an iOS app that enables a nanoparticle-based assay to determine a drug’s toxicity to living tissue. The mobile app essentially provides image analysis to drug screening method that is growing in popularity. The new method aims at replacing in vivo (in living subjects) methods with in vitro (in test tube) tests to determine how drugs affect living tissue. A Houston-based startup, Nano3D Biosciences , has developed just such an in vitro test, dubbed “BiO Assay.” It creates 3-D tissue structures that mimic the results that previously could only be derived from running tests inside living tissue. The method is based on magnetic levitation. A magnetic nanoparticle assembly consisting of gold nanoparticles, poly-L-lysine, and magnetic iron oxide binds to cells. This makes the cells themselves become magnet...

Full article: http://spectrum.ieee.org/nanoclast/biomedical/diagnostics...

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