27 Apr '17, 2pm
OSM (Pronounced Awesome) Hardware Makes DNA in Space
I think that it is either a nice space science student experiment, but without all they features they talk about, or they left out a lot from the science description. In either case I see a lot of unnecessary hype which is not typical for scientific setting. It is not even a synthetic biology problem, or even a problem at all because it is already solved. Arbitrary sequence oligos are the workhorse of molecular biology lab, you can get them for a few bucks. So why the hype? The problem with science I can see is that this will not produce arbitrary sequences in its current form. TdT will be adding nucleotides at random from a mixture of nucleotides. Therefore produced DNA will have random sequence and not arbitrary sequence chosen by you. So, let’s add a little spin and add only one nucleotide at a given time and the then cycle through them. Ok, it could work if the enzyme ...